The new daily service will commence on June 6 and be served by B787 Dreamliner aircraft.
Flights will depart Dublin at 11.50 and arrive in San Francisco at 14.20, with return flights departing at 15.55 and landing in Dublin at 09.45 the following day.
“Dublin and the Silicon Valley are two regions synonymous with big tech,” says Patrick Quayle, United’s Vice President of International Network.
“Many global tech companies have a major footprint in both regions, and they need a carrier with an extensive worldwide network to help conveniently connect their business.
“As the only U.S. airline to serve Ireland from the West Coast, United is uniquely suited to provide the connectivity these companies and economies need to continue thriving.”
United already operates year-round flights from Dublin to New York/Newark and seasonal services to Washington/Dulles and Chicago, and from Shannon to New York/Newark.
The airline has also announced the addition of a sixth daily flight between London Heathrow and New York/Newark from March 29.
As with the existing five daily flights, the additional frequency will be operated by a B767-300ER featuring 46 Polaris business class seats and 22 Premium Plus seats.