This will be the first new service from the UK to Kuwait in 55 years, made possible by a new Air Services Agreement signed last year.
The aircraft will feature business class, economy class and a new premium economy class with a 31-inch seat pitch and complimentary meal.
As well as serving Kuwait, the flights will provide onward connectivity to Dubai, Bahrain and Doha in the Arabian Gulf and to New Delhi in India.
The airline owns and operates Kuwait City Airport’s Terminal 5 where it says it has developed a smooth and straightforward transit experience for passengers.
Jazeera Airways’ Chair, Marwan Boodai, says: “Jazeera Airways has been building a great reputation in the Middle East in the low cost airline sector, offering a strong alternative to the legacy airlines.
“We look forward to serving the UK market, and extending consumer choice to Kuwait and the Gulf, with our value proposition. This is a first for an LCC in the Middle East to fly long-haul, using the A320neo aircraft.”
Prices start from £370 return in Economy, £800 in Premium Economy and £1050 in Business Class.
British Airways and Kuwait Airways also operate daily direct flights to Kuwait from London Heathrow.